It is because overloading the muscle cell with glycogen causes ache and may also result in death of particular person muscle cells. Blood work often shows increased muscle enzyme activity in horses with Type 1 PSSM, often even at relaxation. The hazard of a glycogen overloading arises when affected horses devour plenty of easily digestible carbohydrates like starch or sugar, resulting in a rise in blood sugar ranges, and the muscle cells absorb some of the excess blood sugar and store it in glycogen. Also problematic for affected horses are sudden, excessive efficiency demands - because even when part of their glycogen stores can't be broken down usually, this does not apply to your entire glycogen of the muscle. If strenuous muscular effort causes a depletion of these normally depletable stores, there might be increased formation of recent glycogen throughout the regeneration phase, with abnormal glycogen forming again and overloading the muscle cells. There may be now a simple genetic test to determine whether or not a horse suffers from Type 1 PSSM.
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